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Microglial replacement using Ki20227, a CSF1R inhibitor, in 2HIT mice restored behaviors resembling psychiatric disorders, suggesting a causal contribution of 2HIT stress-reactive microglia, including SAM (Hikosaka et al., 2025)

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Using one needle for both caused itch problem

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First line of biological therapy with golimumab was intensified to 100 mg every 4 weeks in 63.6% (14/22) of the patients with 22.7% (5/22) subsequently dose escalated to 100 mg every other week

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