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The eluted GST was dialyzed overnight against 10 mM TrisHCl pH 7.8, 0.2 mM DTT, 1 mM EDTA and 0.02% (w/v) sodium azide

Diabetes Metab Syndr Clin Res Rev 11:S429S432

Vitamin B12 Vitamin B12 Vitamin B12, also known as cobalamin, is a crucial nutrient that plays a key role in various bodily functions

Minor appearance variations occur naturally between different peptide batches

So, the problem doesnt appear to be directly driven by hyperglycemia but possibly by other factors related to oxidative stress and inflammation two major culprits in chronic diseases like diabetes