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Mechanisms of epigenetic memory

Some studies show shifts in sleep, and others show little or no effect

WQ and YT carried out experiments

In a healthy state, PINK1 is transported into the polarized mitochondria and is subsequently cleaved twice in the mitochondrial inner membrane (MIM) [43,44,45,46]

All controlled studies referenced below were conducted in cell culture (3T3-L1 adipocytes, primary muscle stem cells) or rodent models (diet-induced obese mice, aged C57BL/6J mice)