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However, this activation can also induce cytoskeletal remodeling and reduce cell-to-cell connection integrity in human keratinocytes, highlighting its complex role in tissue homeostasis (71)

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These effects could be attributed, at least partly, to the downregulation of proinflammatory mediators

Cifarelli, V

Depression as a risk factor for Alzheimers disease: A systematic review of longitudinal meta-analyses