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For example, if a clinical trial for an inhaled respiratory medication is conducted before HF validation, subjects may misuse the device (e.g., not holding a button for long enough), resulting in an under-dose

Various NDBs such as chitosan, pectin, -carrageenan, alginate, -polylysine, and others have also been identified for their antibacterial activity (Table 2)

Some claim it degrades within hours, making it ineffective the next day

There is some evidence in rat studies of reductions in oxidative stress as well as improvements in the function of seminiferous tubules in rats

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ONeil PM, et al