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Additionally, downregulation of the suppressor of cytokine signaling 1 led to an elevation of the cytokine level and significant inhibition of tumor growth

GSSG), glutathione can neutralize reactive oxygen species both directly and indirectly (via antioxidant enzymes)

PCA was used to track data quality and to identify and remove outliers in the dataset

All provided p-values are two-sided

It does this without affecting any other enzyme or part of the metabolic cycle (Neelakantan, 2018)

This transcriptional regulatory mechanism represents an important pathway for cells to enhance cystine uptake, promote glutathione synthesis, and thus respond to oxidative damage and maintain cellular redox homeostasis