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Details on used samples number, number of aliquots and technical replicates are described in Supplementary Tables 2 and 3

There was no extractables and leachables profiling

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Proteostasis: maintenance of protein homeostasis in cells, involving processes that regulate protein synthesis, folding, degradation, and clearance to ensure proper protein function and prevent cellular dysfunction and disease

After unloading, the bone returned to its starting position, evidencing that no structural changes were present in the bone and that loading was provided within the elasticity limits of Hook's diagram