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PMID: 33277960

p53 activates the LOX enzyme ALOX12 to induce ferroptosis in cells independent of GPX4 activity (Chu et al., 2019

TNF- activates multiple signaling pathways through binding to its receptors (TNFR1 and TNFR2), inducing the release of inflammatory mediators, cell proliferation, apoptosis, and immune cell recruitment, ultimately leading to chronic intestinal inflammation

The MTT, flow cytometry, and wound healing assays were used to investigate cell viability, cell cycle, and cell migration, respectively

These findings are consistent with those of Phusate (2021) who observed a substantial reduction in thyroxine (T4) and triiodothyronine (T3) levels in male rats after 60 days of GLP exposure, along with a non-significant increase in TSH levels compared to the control group

Paying cash Approximately $550$800 per 30-day supply at retail pharmacy (pharmacy-variable estimate)