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Moreover, it is not clear how an intravenous dose of virus in humanized mice compares with an inoculum during a natural oral exposure

Gpx4 is an essential mammalian glutathione peroxidase, which protects cells against detrimental lipid peroxidation and governs a novel form of regulated necrotic cell death, called ferroptosis

Brian Staiger, PharmD's full answer below , condensed by AI from that answer only (not from any outside source)

As a general rule, IM is favored when the goal is rapid correction of a clinical deficiency, when the patient has difficulty absorbing B12 through oral or sublingual routes, or when a provider wants predictable peak serum levels

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