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In terms of fatigue, depression and anxiety, all of those improved, on average, for the intervention group, while slightly increasing for the control group

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The placebo was 97% water and also contained a small amount of beta-carotene for coloring, and citric acid and a proprietary blend of natural plant-based flavors to create a vitamin-like after-taste

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382,383 An in-depth understanding of the underlying mechanisms of cellular pyroptosis is essential to determine its role in the pathogenesis of DPN and develop effective therapeutic agents targeting the pyroptosis signaling pathway to alleviate neuropathic symptoms

19 However, this intervention faces challenges of safety and limited efficacy for inducing rejuvenation in vivo