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10.1016/j.chembiol.2018.11.016 103 MantovaniA.SchioppaT.PortaC.AllavenaP.SicaA

Change history 16 April 2015 This article has been corrected since Online Publication and a corrigendum has also been published Abbreviations ACNU: nimustine BSO: buthionine sulfoximine CNU: chloroethylating nitrosourea CTR1: copper transport channel DSBs: double-strand breaks GSH: glutathione GST: glutathione S -transferase HCR: host-cell reactivation ICL: interstrand crosslink MGMT: O 6 -methylguanine-DNA methyltransferase NAC: N -acetyl cysteine NER: nucleotide excision repair (O 6 MeG): O 6 -methylguanine TMZ: temozolomide References Wen PY, Kesari S

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Development and characterization of continuous avian cell lines depleted of mitochondrial DNA

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For example, if you always want to draw 50 units (0.50 mL) per dose for consistency: At 2.5 mg dose: Reconstitute for 5 mg/mL (2.5 divided by 5 = 0.50 mL) At 5 mg dose: Reconstitute for 10 mg/mL (5 divided by 10 = 0.50 mL) At 7.5 mg dose: Reconstitute for 15 mg/mL (7.5 divided by 15 = 0.50 mL) This "consistent draw" approach reduces the chance of dosing errors when transitioning between dose levels because you always draw the same volume