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Radiation enteritis (RE) model WT mice were anesthetized by intraperitoneal injection of 50 mg/kg Zoletil 50 (virbac) and 5 mg/kg Xylazine Hydrochloride (D005, Jilin Huamu Animal Health Product Co., Ltd.), then treated with total abdominal irradiation with a single irradiation dose of 16 Gy (-ray) at a rate of 1.0 Gy/min in a Siemens Primus Plus (SIEMENS, Germany) to establish a radiation enteritis (RE) model

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There are two types of synthetic B12

Standard: 40 mg loading (weeks 14) + 20 mg maintenance (weeks 512) = 60 mg total (12 5 mg vials)

This stabilizes the oxidant and lowers the cells oxidative status