Ca 2+ plays an important role in promoting fatty acid catabolism by stimulating downstream enzymes in the Krebs cycle indicating that the formation of MAMs and the subsequent increase in mitochondrial Ca 2+ may exert a short-term beneficial effect by increasing fatty acid -oxidation
When these are slow or saturated, more is shunted to CYP2E1, producing the reactive NAPQI intermediate
Madalina (5 g/kg), rich in sinapine, glucosinolates, and flavonol glycosides, brought about anxiolytic and antidepressant effects in stress-induced irritable bowel syndrome mouse models (140)
To view a copy of this licence, visit About this article Cite this article Hatzichristou, D
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