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The first mammalian regulator of apoptosis emerged when bcl-2 , the gene activated by chromosome translocation in human follicular lymphoma [131] was unexpectedly found to permit the survival of cytokine-dependent hematopoietic cells, in a quiescent state in the absence of exogenous cytokine [132]

The miR-522 inside exosomes, generated from cancer-associated fibroblasts (CAFs), can block lipid-ROS accumulation by targeting ALOX15 and thus inhibit ferroptosis (Zhang H

Some miRNAs, such as miR-489-3p and miR-375, can directly target SLC7A11 and trigger ferroptosis (Ni H

Pingault L, Choulet F, Alberti A, Glover N, Wincker P, Feuillet C, Paux E (2015) Deep transcriptome sequencing provides new insights into the structural and functional organization of the wheat genome

Then, 50 l of the sample was mixed with 5 l of 3 mM DTT and incubated for 1 h at RT in darkness

So why use it at all