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10.3390/ijms25115587 17 ArnoldS

Catalytic organometallic anticancer complexes

The reaction formula can be summarized as follows: 2 GSH GSSG + 2H + 2e (under the action of GPX or ROS) However, to prevent GSSG accumulation from disrupting the intracellular sulfhydryl balance, cells need to rapidly convert it back to GSH through an efficient reduction system

These TF binding sites were not identified in the corresponding regions of S.cerevisiae S288c (Figures 3b and 3c)

Rodrguez F, Caruana P, De la Fuente N, Espaol P, Gmez M, Balart J, et al