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10.1093/hmg/ddab162 126 SalemY.RajhaH

Patients with symptoms experience headache, fever, myalgia, regional lymphadenopathy, and tender genital vesicles

Additionally, environmental stressors can disrupt the skins moisture balance, leading to dryness, redness, and an overall lack of radiance

Clear correlation with the luteal phase: Symptoms consistently worsen during the luteal phase , when progesterone peaks, and are absent or significantly improved during the follicular phase when progesterone is low

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