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Inflammatory markers at baseline and weeks 6 and 12

Kambe, T., Matsunaga, M

Cohen's d = 1.03

Each drug hits certain pathways and there are clues there: Nicotine and stimulants - acetylcholine and glutamate (so maybe reduced glutamate, to begin with) Benzos - GABA (so maybe too much glutamate) Alcohol - GABA and serotonin (plus just about everything) a depressant so too much glutamate