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[DOI] [PubMed] [Google Scholar] Lucena GM, Franco JL, Ribas CM, Azevedo MS, Meotti FC, Gadotti VM, Dafre AL, Santos AR, Farina M

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With the development of IR, an unfavorable, reverse flux of FFAs toward non-adipose tissues, such as the liver, occurs

In situations when there is poor insulin response such as type 2 diabetes mellitus or insulin resistance, the process of gluconeogenesis continues even in the fed state, thus, further compounding hyperglycemia (32)

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Others, more delicate, demand precise care to avoid falling apart