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Effect of long-term vitamin D3 supplementation vs placebo on risk of depression or clinically relevant depressive symptoms and on change in mood scores: a randomized clinical trial

1425-C INTERFERON-BASED THERAPIES ARE BENEFICIAL IN CIRRHOTIC HEPATITIS B PATIENTS WITH GOOD LIVER FUNCTION RESERVE: REAL-WORLD EVIDENCE FROM OASIS PROJECT 2.5-YEAR DATA Qiran Zhang 1 , Feng Sun 1 , Yiqi Yu 1 , Shulan Sui 1 , Tingting Zhao 1 , Ying Guo 2 , Wanhua Ren 3 , Jiming Zhang 4 , Yuxian Huang 1 and Wenhong Zhang 1 , (1)Huashan Hospital, Shanghai Medical College, Fudan University, (2)The Third Peoples Hospital of Taiyuan, Taiyuan, China, (3)Shandong Provincial Hospital Affiliated to Shandong University, (4)Fudan University Background: Interferon (IFN)-based therapies are considered effective in functional cure and reducing hepatocellular carcinoma (HCC) risks in patients with chronic hepatitis B (CHB)