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Although, there are other ROS, such as organic hydroperoxides (ROOH), peroxyl radical (ROO), alkoxyl radical (RO), singlet molecular oxygen ( 1 O 2 ), and ozone (O 3 ), that also play essential roles in signaling and disease (Sies and Jones, 2020)

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Allergic sensitization: host-immune factors

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The resulting pressure differential pulls contaminants back through the needle on every subsequent draw, introducing bacterial spores or particulate matter that wouldn't breach a properly vented system