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The solution was then lyophilized (Sub Zero Lyophilizer, China) at -40 C for 8 h after being purified by dialysis (12,000 kDa molecular weight cutoff [MWCO], Himedia, China) against DD water for 48 h

Potential Mechanisms of THC on Neuroprotection and Repair Antioxidation THC expedites the clearance of free radicals within the body by activating a suite of antioxidant enzymes, including superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), catalase (CAT), and glutathione S-transferase (GST), thereby reinforcing the stability of the brains antioxidant enzyme system [5]

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In senescent ECs, increased LD accumulation was linked to elevated expressions of proinflammatory cytokines [91]

Neurology 62:17581765 Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascon S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD (2017) Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease