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Taken together, these findings suggest thatcontrary to initial assumptionscomplex II may contribute to ferroptosis not by protecting cells via ubiquinol (CoQ 10 H 2 ) production but by promoting mitochondrial ROS accumulation

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(6.1) The most common adverse reactions (incidence 20%) of pemetrexed when administered with cisplatin are vomiting, neutropenia, anemia, stomatitis/pharyngitis, thrombocytopenia, and constipation