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Meanwhile, to investigate the GSH responsiveness and the function of BSO, the control peptide derivative Nap- D F D FY-HDA-DEVD-BSO (NCBSO) and peptide derivative without BSO Nap- D F D FY-CS-DEVD (NS) were prepared respectively in a similar way (Fig

This process primarily occurs in the liver, the bodys main organ for detoxification.[ref] The CYP450 enzymes have iron and oxygen in them and, through a redox reaction, can make a drug, toxin, or endogenous substance more polar

Brouillard, R

Th17-derived cytokines also promote intracellular iron accumulation and glutathione depletion in structural lung cells, accelerating ferroptotic damage (132)

Science 337 , 975980 (2012)

The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response