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Diabetes Care 36(10):29812987 Wakeman M, Archer DT (2020) Metformin and micronutrient status in type 2 diabetes: does polypharmacy involving acid-suppressing medications affect vitamin B12 levels

doi: 10.1016/j.drudis.2018.01.047

In this study, accumulation of lipid peroxidation end products MDA and 4-HNE and intracellular iron coincided or preceded with the hepatocellular injury in the Aldh2*2 KI mice after AA exposure, suggesting that ferroptosis is involved in the exacerbation of liver injury [56,77]

Similarly, homozygous deletion of both these genes seemed to have no influence on CML pathogenesis during the present study (Table 2)