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Cardiolipins are specific phospholipids of the mitochondrial inner membrane that participates in many aspects of its organization and function, hence promoting proper mitochondrial ATP production (Prola and Pilot-Storck, 2022)

Therefore, we hypothesize that deregulated homocysteine metabolism in homocystinuria with severe hyperhomocysteinemia will lead to the cyclization of homocysteine into homocysteine thiolactone, which may render LDL less susceptible to oxidation

Emotions are energy in motion

Cuproptosis can modulate the expression of key genes involved in ferroptosis regulation, such as glutathione peroxidase 4 (GPX4), by eliminating phospholipid hydroperoxides [123, 124] and acylcoenzyme A synthetase long-chain family member 4 (ACSL4) [125], thereby regulating the sensitivity of cells to ferroptosis inducers

PC2 score plot for all the samples, however, the PCA distribution did not identify a valid separation between the HC and ASD groups

Parents rated intervention response using a modified Clinical Global Impression Improvement type scale called the Parent Rated Autism Symptomatic Change (PRASC) scale