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doi: 10.1016/s0735-1097(99)00216-8

Potential Roles for Vitamin C in Genomic Stability via Modulation of Additional -KGDDs Vitamin C can participate as a cofactor to enhance and maintain the activity of numerous other -KGDD family members, such as histone lysine demethylases (KDMs), hypoxia inducible factor (HIF) prolyl hydroxylases, and AlkB homologs (ALKBHs), in addition to TET proteins, that in combination can influence genomic stability

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In the liver, NK cells sustain metastatic breast cancer cell dormancy through IFN- signaling