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-mangostin treats early-stage adjuvant-induced arthritis of rat by regulating the CAP-SIRT1 pathway in macrophages

Zhang, W., Trachootham, D., Liu, J., Chen, G., Pelicano, H., Garcia-Prieto, C

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2297-C DEVELOPMENT OF A NOVEL IN VITRO MITOCHONDRIAL TOXICITY TEST BASED ON ATP INHIBITION SUBSTRATE ASSAY Hyunwoo Oh 1 , Hyo Young Lee 1 , Eileen Yoon 2 , Huiyul Park 3 , Sang Bong Ahn 4 , Joo Hyun Sohn 2 and Dae Won Jun 2 , (1)Uijeongbu Eulji Medical Center, (2)Hanyang University College of Medicine, (3)Hanyang University, (4)Eulji Medical Center Background: Mitochondrial toxicity has led to the withdrawal of numerous drugs from the market, highlighting the importance of assessing mitochondrial dysfunction during drug development

Emerging role of miR-21 in non-alcoholic fatty liver disease