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60, 61 CTP1C expression displays an inverse correlation with the activation of mTOR pathway and attenuates tumor sensitivity to rapamycin (a mTOR inhibitor), 18 which suggests that the CPTIC-involved pathway parallels to mTOR-enhanced glycolysis

10.1371/journal.pone.0089189 PLoS One 64 ScheweT

This is a particularly interesting possibility given that diet might be a significant contributing factor to ASD risk associated with TMLHE mutations

The bell-curve dose-response means starting low and titrating to the individual response is more important than with other peptides