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Direct injection can damage peptide structure through mechanical stress

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In suspected cyanide-poisoned patients, we recommend the use of hydroxocobalamin as first-line antidote, owing to its safety

Wang J, Obici S, Morgan K, Barzilai N, Feng Z, Rossetti L

FACT 3 OF 6 IM injections for severe deficiency or absorption failure If your sublingual dose doesnt maintain serum B12 above 400 pg/mL, switch to intramuscular injections: 1,000 mcg monthly (more often initially if very deficient)

B12s most prestigious role is in the methylation cycle, which co-stars Folic Acid

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