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Description

(PubMed) Seshadri S, Beiser A, Selhub J, et al

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(2000) Metabolic Studies of a Synthetic Lipolytic Domain (AOD9604) of Human Growth Hormone Horm Res 53(6):274278

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As fat cells expand, they begin to produce more NNMT, an enzyme that disrupts normal metabolic function

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The trial proceeded without reported toxicity, and no lethal dose threshold (LD1) was ever established in subsequent safety testing meaning researchers administering the compound could not find a dose that caused death in even 1% of test subjects across the animal model safety work that preceded and followed the human study

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