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Elevated levels of these reducing agents have been linked to a range of issues, from diminished oxidative capacity and tissue damage to an unexpected surge in ROS [215]

Pharmacotherapeutic evidence Postmortem frontal cortex analyses showed higher ETC complex I in people with BD receiving lithium than those not receiving lithium [47]

DNA methylation induces ferroptosis in tumor cells by regulating GPX4, a key molecule in ferroptosis

Free Radic Biol Med 32:10501060

DOI: 10.1186/1741-7015-12-85

This process is accompanied by the activation of NOD-like receptor thermal protein domain-associated protein 3(NLRP3) inflammatory vesicles and the formation of neutrophil extracellular trapping networks (NETs), which exacerbate corneal epithelial damage and persistent microbial infection