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Small doses of short acting narcotics can be used for "breakthrough" pain

Long-term use: Using Neurobion injection for more than six months continuously may cause B6-related nerve damage

doi: 10.1055/s-0033-1337335

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This review was achieved using PubMed and the following key words: VEGF, VEGF signaling pathway, angiogenesis, cancer, immune response, innate immune response, adaptive immune response, macrophages, natural killer, neutrophils, mast cells, myeloid-derived suppressor cells, dendritic cells, T-cells, therapy, therapy resistance