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Biopolymer: a sustainable material for food and medical applications

The primer sequences were provided in Supplementary Table S2

According to the substrate scope assay, the mutant was also classified as a CO since it did no longer accept tyramine and L -tyrosine (Fig

A single ABCD1mutation does not clearly explain the severity and diverse clinical spectrum of X-ALD phenotypes which suggests that not only genetic but also other modifier genes, epigenetic factors, and environmental factors play a role and contribute to neuroinflammation, mitochondrial dysfunctions, oxidative stress, and metabolic defects seen in phenotypes of ALD