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Hospital La Paz Institute for Health Research IdiPAZ (La Paz University Hospital Universidad Autnoma de Madrid), Madrid, Spain, 2 Stroke Code Coordination Center, Servicio de Emergencias Mdicas SUMMA-112, Madrid, Spain, 3 Department of Neurology, Hospital Universitario Clnico San Carlos, Universidad Complutense de Madrid, Madrid, Spain, 4 Department of Neurology and Stroke Center, Hospital Universitario 12 de Octubre, Instituto de Investigacin Hospital 12 de Octubre (i+12), Madrid, Spain, 5 Department of Neurology, University Hospital Puerta de Hierro, Universidad Autonoma de Madrid, Madrid, Spain Background and Aims: In our stroke network, direct transfer to mechanical thrombectomy (MT) center (MT-C) instead of nearest non-MT-capable stroke unit (NSU) is determined by an M-DIRECT score 2

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In addition, increasing STAT3 from activated JAK/STAT signaling pathway might be involved in the apoptosis of cell through PTEN, which inhibits Akt cascade, resulting in exacerbated hyperglycemia 136 (Fig

Moreover, its defined amino acid sequence allows researchers to examine targeted molecular interactions in vitro

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