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Targeted MRM-based methods are most easily developed with the availability of purified proteins, whereas untargeted DDA analyses offer a more flexible, universal application without time-consuming optimization steps

10.1016/j.cell.2013.12.010 119 YangX.LiY.ZhangY.LiuJ

Hosono, A., Tanabe, T., & Otani, H

These include hot flashes, night sweats, mood swings, anxiety, or irritability

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Cousijn H, Haegens S, Wallis G, Near J, Stokes MG, Harrison PJ, Nobre AC (2014) Resting GABA and glutamate concentrations do not predict visual gamma frequency or amplitude