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doi:10.1371/journal.pone.0261552

Depression and Mood Disorders: Multiple high-quality studies, including meta-analyses, have demonstrated that ALCAR may be as effective as certain prescription antidepressants for cases of mild to moderate depression, often presenting with superior tolerability

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Moreover, a study by Lopez and collaborators found that patients with constipation tended to have higher incidence of hypokalemia but these results didnt reach statistical significance 30