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These functional declines are compounded by dysfunctional signaling in TLR2 and TLR4 pathways, further impairing immune responses in the elderly [259]

10.1186/2040-2392-4-14 256 SarachanaT.XuM.WuR

2008;6:e182

Volodymyr Lushchak (Ed.), 2012, ISBN: 978-953-51-0552-7, InTech, Available from: Mnzel T, Camici GG, Maack C, Bonetti NR, Fuster V, Kovacic JC

These emerging therapies target a wide range of conditions and employ novel mechanisms of action

Liposomes are spherical vesicles with one (unilamellar) or more (multilamellar) phospholipid bilayers encapsulating an aqueous core, with polar head groups, DOTMA (1,2-di-O-octadecenyl-3-trimethylammonium-propane), and DOTAP (1,2-dioleoyl-3-trimethylammonium propane), and zwitterionic DOPE (dioleoylphosphatidylethanolamine)