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Cardiac Excitation-Contraction Coupling Alterations Induced by LCACs Cardiomyocyte contractility and electrophysiology, and the induction of arrhythmias, is dependent on a paradigm of ion-handling processes known as excitation-contraction coupling (ECC)

If possible, nonpharmacological approaches that would not be burdensome for patients may be a promising solution for patients with cachexia, who are affected by fatigue, decreased energy levels, nausea, and decreased appetite.

Ter Horst KW, Gilijamse PW, Versteeg RI, Ackermans MT, Nederveen AJ, la Fleur SE, Romijn JA, Nieuwdorp M, Zhang D, Samuel VT, Vatner DF, Petersen KF, Shulman GI, Serlie MJ (2017) Hepatic diacylglycerol-associated protein kinase cepsilon translocation links hepatic steatosis to hepatic insulin resistance in humans

Magnesium citrate is a magnesium salt of citric acid, commonly used due to its excellent absorption rate

Key pathways affected by folate include one-carbon metabolism and the transsulfuration pathway, both essential for proper neurodevelopment

Jones ME, et al