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Individual side effects (nausea, injection-site reactions) can occur with either agent alone, but combined use raises localized inflammation risk from frequent injections

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While glutathione does not directly lower glucose, studies suggest supplementation may improve insulin sensitivity

Acknowledgements We apologize to the researchers who were not referenced owing to space limitations

Collectively, these antioxidants alleviate renal anemia by reducing premature erythrocyte death, prolonging erythrocyte lifespan in circulation, and addressing the oxidative stress imbalance inherent to CKD, making them promising adjuvant therapeutic agents alongside conventional EPO or iron supplementation