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Research has shown that 40 to 90% of RLS cases have at least one first-degree relative with RLS

In murine models, NNMT knockdown did not induce the accumulation of NAM in livers and adipose tissues, nor did it cause significant alterations in the intracellular levels of NAD + in hepatocytes (Kraus et al., 2014

Side Effects and Safety Profile The extensive clinical development program for AOD-9604 included rigorous safety assessment across animal toxicology studies and human trials, providing a comprehensive understanding of the peptides safety profile