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Metabolic adaptation of the cellular component of the BM niche induces a HIF1-dependent glycolytic program, which increases CD73 and ADOR expression ( + ) (Figure 1, after consuming glucose at a higher rate than normal cells, MM cells secreted most of the derived byproducts as lactic acid, a phenomenon known as the Warburg Effect ( + ) results in acid accumulation within MM cells

Cells were plated in 6 cm plates (600,000 cells/plate)

Some alcohol, approximately ten (10%) percent, is eliminated through sweat, breath, and urine

The GSSG/GSH ratio is therefore a good indicator of good cellular health and a decrease in its value is a sign of major cellular dysfunction 27,28

The health risks are definitely on my mind, but in saying that, everythings bad for you