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doi: 10.1038/s41598-020-69016-9 79 CaoYWangHWangQHanXZengW

Experiments were executed at 25C in the early afternoon

d ) lyso-H 4 B-CH 3 (10 nM) and lysoTracker DR (75 nM) to show lysosomal localization of lyso-H 4 B-PMHC

To further elucidate the catalytic mechanism of how P300-mediated H3K18la, we performed molecular docking analysis using Autodock Vina to investigate the interaction between P300 and lactyl-CoA (PubChem: 1926-57-4), aiming to determine their binding mode and active sites (Fig

Clinical Results

At the same time, receptor or molecule attachment to the surface of liposomal nanocarriers can be used to construct molecular probes with targeting properties [103, 104]