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Moreover, a multicentric, double-blind, placebo-controlled, randomized trial that used the same methodology found that in patients who are suffering from stage I or II HNSCC and on radiation therapy while taking 400 IU of -tocopherol daily had a significantly higher incidence of subsequent primary malignancies (60/1000 person-years) compared to those on placebo (25/1000 person-years)

10.3389/fcimb.2014.00050 87 EckerJ.LiebischG.EnglmaierM.GrandlM.RobenekH.SchmitzG

All pts who received ate/bev permanently discontinued treatment due to side effects including bleeding

heart rate, 100/min

It acts as both a pain reliever and a fever reducer

Cluntun AA, Lukey MJ, Cerione RA,Locasale JW