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While TAU's affinity for isolated lysosomes may not be perfectly tailored for CMA substrate interaction, truncated TAU mutants do not completely translocate into the lysosomal lumen for degradation, despite the existence of two CMA targeting motifs in TAU C-terminal region (179)

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The luciferin formed is detected in a coupled reaction using Ultra-Glo Recombinant Luciferase that generates a glow-type luminescence that is proportional to the amount of glutathione present in cells

Inhibition of the mPTP and lipid peroxidation is additively protective against I/R injury

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Compared to mice given free GSH, whey encapsulated GSH resulted in significantly increased antioxidant capacity in the plasma through the entire period of study (from 15 minutes until 240 minutes after ingestion).* Non-toxic In the 28-day toxicology arm of the study, a diet containing up to 4% GSH in a whey protein matrix was found to be safe and non-toxic