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In contrast, the homozygosity rate of this SNP was found to be only 4% in the control population

Indeed, CEBPB and EP300 , along with genes related to the Mitogen-Activated Protein Kinase (MAPK) signaling cascade such as MAP3K1 , MAP2K2 , and MAP3K11 were significantly upregulated in RMC tumor cells following treatment with nivolumab plus ipilimumab, (Fig