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Rohle D, Wilborn C, Taylor L, Mulligan C, Kreider R, Willoughby D

m6A demethylase ALKBH5 reduces ferroptosis in diabetic retinopathy through the m6A-YTHDF1-ACSL4 axis

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However, since the discovery of alternative pathways for PDI reoxidation (Frand & Kaiser, 1999

CRISPR/Cas9-mediated gene editing Single guide RNA sequences targeting SLC27A5 and GSR were designed (Table S1) using the E-CRISP ( and cloned into the Cas9-expressing lentiviral vector CRISPRv2 (Prof

In patients with depression or animal models, significant alterations in iron content or iron-related genes associated with ferroptosis have been observed [134], indicating that abnormal iron metabolism in the brain may contribute to the pathophysiological changes of depression [11,134]