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on reuptake) develop within a matter of hours

The mechanism involves positive regulation of the expression of ALDHs and cytoprotective enzymes (e.g

Reduced autophagic activity not only leads to the delayed and abnormal accumulation of denatured proteins and dysfunctional organelles but also, through various pathways, results in endothelial dysfunction and intimal thickening, exacerbating vascular aging

Jenner P (2003) Oxidative stress in Parkinsons disease

Additionally, GSH shifts the melanogenesis pathway away from eumelanin (the darker brown/black pigment) toward pheomelanin (the lighter red/orange pigment) by interacting with dopaquinone intermediates in the Raper-Mason pathway

doi: 10.1016/j.bbrc.2022.01.106 201 MuriJ.KopfM