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Increased oxidative stress and ROS overproduction may cause not only endothelial dysfunction but also programmed ECs death such as ferroptosis, pyroptosis, or necroptosis that are involved in the pathophysiology of many diseases, like COPD [78]

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Asian J Pharm Clin Res 10(5):313317 Abdellatif NA, Eltamany EE, El-Shenawy NS, Nafie MS, Hassan YM, Al-Eisa RA, Badr JM, Abdelhameed RF (2024) Cassia fistula leaves extract profiling and its emphasis on induced ulcerative colitis in male rats through inhibition of caspase 3 and cyclooxygenase-2

Numerous studies have verified the role of the HGF/c-MET pathway in sustaining an immunosuppressive TME, as it obstructs CTL activation and promotes CTL exhaustion (Fig

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The associations observed in the NHANES data may be influenced by reverse causation or residual confounding factors, such as poorer general health status or medication usage, leading individuals to sleep longer durations