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Ann Rheum Dis (2013) 72(3):33744

Identification of PKA subunits as central hubs in network modules for synapse formation regulated by AKAP11 To gain an insight of the relationship among cellular pathways/functions affected by the loss-of-function in AKAP11 as an autophagy receptor, we employed the modified Weighted Gene Co-expression Network Analysis (WGCNA) 39,40 to dissect proteomics data from Akap11 -cKO mouse brains and human AKAP11 -KO iNeurons