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[18] While higher levels of homocysteine have been associated with numerous health complications, levels of homocysteine that are too low can also be problematic and have been associated with peripheral neuropathy (often felt as hand and arm tingling) and an impaired ability to make glutathione, an important antioxidant that reduces inflammation in the body

Hormone replacement therapy addresses estrogen, progesterone, and in some protocols testosterone directly

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Disease stage and remaining tissue considerations Early disease with substantial viable tissue: Maximum benefit from protective mechanisms

Type 1 is the enzyme variant primarily responsible for converting testosterone to DHT in hair-damaging locations, and this inhibition occurs with greater specificity for the hair-relevant type 1 than the prostate-relevant type 2